T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Fibroblasts are the most common cell found in connective tissue. A fibroblast synthesizes the collagen and ground substance of the extracellular matrix.
A fibroblast is often spindle-shaped (or fusiform) with an elongated nucleus. Active fibroblasts can be recognized by their abundant rough endoplasmic reticulum (RER) and prominent Golgi apparatus.