T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The lumenal surface of the small intestine is covered by simple columnar epithelium with goblet cells.
Surface Absorptive Cells (Enterocytes)
Surface Absorptive cells (left and right; dark green) are the predominate cell type in the intestinal epithelium. They are specialized for the absorption of nutrients.
Microvilli (dark green) - expands the surface area for absorption
Cytoplasm (dark green)
Goblet Cells
Goblet cells (center) secrete mucins (main component of mucus). Their goblet shape is due to secretion granules expanding the apical region of the cells.
Microvilli (dark green) - expands the surface area of the apical surface for absorption
Cytoplasm (light green)
Lymphocytes
Lymphocytes (examples, #1 and #2) are immune cells that are prevalent in the gastrointestinal tract. They are components of gut-associated lymphoid tissue (GALT).
Lymphocytes (examples, #1 and #2) extend pseudopodia to infiltrate the epithelium through openings in the basal lamina.