T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The lumenal surface of the small intestine is covered by a simple columnar epithelium with goblet cells.
Goblet Cells
Goblet Cells (dark green) secrete mucins (main component of mucus). Their goblet shape is due to secretion granules expanding the apical region of the cells.
Secretion Granules (purple) - large, densely packed in the apical region of the cell.
Golgi Apparatus (yellow) - well developed in this secretory cell.
The lumenal surface of the small intestine is covered by a simple columnar epithelium with goblet cells.
Surface Absorptive Cells (Enterocytes)
Surface Absorptive Cells (enterocytes; light green) are the predominate cell type in the intestinal epithelium. They are specialized for the absorption of nutrients.
Microvilli (green) - thin extensions that increase the surface area of the apical membrane.
Terminal Bar - complex of tight junctions (zonula occludens), zonula adherens and desmosomes (maculae adherens).
Mitochondria (red) - provide energy for the transport of molecules
The lateral plasma membranes of adjacent cells have extensive interdigitations.
Basal Lamina (dark purple) - thin, fuzzy line that separates the epithelium from the underlying connective tissue. A network of reticular collagen IV fibrils.
