T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Gastric epithelium isolated from the pyloric antrum of the stomach (SEM). The lamina propria has been removed exposing the pyloric glands.
Pyloric glands are relatively straight but are coiled near the muscularis mucosae. The linear appearance seen here is from the absence of the lamina propria which maintains their shape.
Morphology of pyloric glands:
Surface Mucous Cells (blue) - simple columnar epithelium that produces mucus to protect the epithelium from gastric acid and proteolytic enzymes
Gastric Pits - deeper than gastric pits in other regions of the stomach
Pyloric Glands (yellow) - simple or branched tubular glands that open into gastric pits
Mucous Cells - similar in appearance to surface mucous cells
Enteroendocrine Cells - scattered among the mucus-secreting cells
G Cells - secrete gastrin which stimulates parietal and chief cells