T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Although respiratory epithelium is a single layer of cells, the nuclei are not aligned in the same plane. This can appear as several layers of cells. Some of the cells also have cilia. Thus, it is classified as a ciliated, pseudostratified columnar epithelium.
This section of a ciliated cell does not contain its attachment to the basal lamina.
Nuclei (blue) / Nuclear Envelope (purple)
Mitochondria (red)
Endoplasmic Reticulum (cyan)
Cytoplasm (green)
Cilia (green) - the nine outer doublets and two central singlets of microtubules are seen in cross sections of cilia.
Basal Lamina (purple) - thin, fuzzy line that separates the epithelium from the underlying connective tissue. A network of reticular collagen IV fibrils.
An immune cell (tan) can be seen at the bottom of the epithelium. (Lymphocytes can cross a basal lamina and move into an epithelium.)