T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The monolayer of flattened cells rests on a thin basal lamina supported by connective tissue.
Basal Lamina (dark purple) - an underlying network of reticular collagen IV fibrils. It appears as a dark line that separates the epithelium from the underlying connective tissue.
Connective Tissue (grayscale) - collagen fibers are seen in both cross and longitudinal sections.
Tight Junctions
Tight junctions (also known as zona occludens) form sites where the plasma membranes of adjacent cells come very close together. This forms an impermeable barrier to materials and fluid.
A small portion of another cell can be seen at the top of this image. The tight junctions appear as darker material along the plasma membranes of the two cells.