T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The extracellular matrix of hyaine cartilage is produced chondroblasts. When they become surrounded by matrix they are known as chondrocytes.
Chondrocytes (purple) - its surface is covered with numerous, small extensions
Lacunae (dark blue) - the space occupied by the individual chondrocytes (empty lacunae result from the removal of chondrocytes during fracturing of the specimen)
Cell nests (light blue) - recently divided chondrocytes occupy the same or very closely adjacent lacunae
Matrix (blue) - loose network of type II collagen fibrils and chondroitin sulfate
Hyaline cartilage contains no blood vessels or nerves.