T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Fibroblast from the adult dermis shows typical morphology of an active cell synthesizing the major structural proteins.
Collagen fibers - bundles of collagen fibrils wich are themselves aggregates of collagen molecules
Longitudinal Sections (blue) - collagen fibrils have a 68 nm banding pattern because the collagen molecules are staggered to adjacent collagen molecules within fibrils
Cross Sections (blue) - diameter of collagen fibers are relatively constant and varies between tissues
Elastic fibers (purple)- can stretch up to 1.5 times its length
Decreases in the dermis with aging because of exposure to ultraviolet light