T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The wall of the small intestine contains two orthogonal layers of smooth muscle.
Inner Layer - individual cells vary in diameter depending on their location within the cell. Cross-sections through the middle of cells have centrally located nuclei, usually surrounded by an unstained region.
Outer Layer - in relaxed smooth muscle, the nuclei are elongated with rounded ends. When contracted, the nuclei spiral, kink, or twist. The cytoplasm is pink, unstriated and with little detail.
Compare the smooth muscle to the adjacent layers of collagen fibers.