T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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This review shows the different types of blood cells identified in the previous slide.
Red Blood Cells (RBCs, erythrocytes) - light red, biconcave discs (~7.5 µm diameter) without nuclei.
Platelets - small, basophilic discs (2 to 4 µm diameter).
White Blood Cells:
Neutrophils (polymorphonuclear leukocytes, PMN) (#1, #2, #3, #4#5) - have distinctive nuclei with 2 to 5 lobes (polymorphic) and azure granules. Specific granules are unstained.
Eosinophils (#1, #2, #3 and #4) - contain distinctive large, eosinophilic granules. Nuclei usually have two lobes.
Basophils (#1 and #2) - rare cells with distinctive large, basophilic granules.
Lymphocytes - occur in a range of sizes.
Small Lymphocytes (#1, #2 and #3) - small cells (6 to 9 µm diameter) with a thin rim of cytoplasm. Nuclei are round and densely stained heterochromatin.
Large Lymphocytes (#1, #2 and #3) - larger cells (9 to 15 µm diameter) with more cytoplasm than small lymphocytes. Nuclei contain a mixture of euchromatin and heterochromatin.
Monocytes (#1, #2 and #3) - large cells (12 to 20 µm diameter) with "kidney-shaped" or notched nuclei with chromatin having a "raked" appearance. The cytoplasm is bluish-gray.