T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The parotid is a major salivary gland. It secretes primarily serous (protein) fluid and little mucous (carbohydrate).
Stroma - the connective tissue component of the gland.
Capsule - connective tissue that encapsulates the gland.
Lobes - connective tissue divides the gland into lobes.
Lobules - connective tissue further divides lobes into lobules - the smallest functional unit.
Parenchyma - the functional component of the gland that consists of secretory cells and ducts
Serous Cells - arranged in acini of pyramidal serous cells. These polarized cells have RER at their base (basophilic) and secretion granules (eosinophilic) at their apex
Mucous Cells - polarized cells with flattened nuclei at the bottom of the cells. They are very lightly stained with a "foamy" appearance (mucous has been extracted).
Intralobular Ducts - two types are found within lobules:
Intercalated Ducts (#1, #2 and #3) - the smallest ducts that insert into and drain individual acini. They are more lightly stained than acini cells and are low cuboidal.
Striate Ducts - arise from intercalated ducts. They are columnar with basal striations and are surrounded by capillaries.
Interlobular (or Extralobular) Ducts (#1 and #2) - found outside of lobules.
Simple columnar, stratified columnar or stratified cuboidal epithelium.
