T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The gastroesophageal (or cardioesophageal) junction is the boundary between the esophagus (right) and the cardiac region of the stomach (left). Although an anatomical sphincter is not present, the normal function of this junction prevents the reflux of stomach acid into the esophagus.
Both the esophagus and stomach are composed of the four layers characteristic of the gastrointestinal tract. The layers are continuous across the gastroesophageal junction: