T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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The gastroduodenal junction is the boundary between the pyloric stomach (left) and the duodenum (right) of the small intestine. The pyloric sphincter controls the passage of chyme from the stomach into the duodenum.
The stomach and the duodenum are composed of the four layers characteristic of the gastrointestinal tract. However, pyloric glands are located in the mucosa whereas the duodenal glands are located in the submucosa. This can easily be seen by following the muscularis mucosa across the gastroduodenal junction.