MH 151 Thyroid

MICROSCOPE SLIDE

SLIDE NAME

MH 151 Thyroid

TISSUE

THyroid

STAIN

Hematoxylin & Eosin

IMAGE SIZE

59,430 x 31,613 pixels
7.0 GB

FILE SIZE

314 MB

MAGNIFICATION

40x

PIXEL SIZE

0.3171 µm

SOURCE

Medical Histology Collection

CONTACT

Questions or comments should be sent to
tcbrelje@gmail.com

This web site is owned and operated by:

T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Version 4.2

© 2005-2019.
T. Clark Brelje and Robert L. Sorenson.
All rights reserved.

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MH 151 Thyroid

Thyroid

The thyroid gland is a bilobed endocrine gland. It is unique in that it stores its hormones bound to an extracellular pool of protein (colloid).

Stroma

Capsule - enclosed by a thin layer of connective tissue.
Trabeculae - connective tissue extends inwards from the capsule to partially outline irregular lobes and lobules.

Parenchyma - secretory follicles constitute the functional units of the gland.

Thyroid Follicles - spherical follicles of varying size (50 to 500 µm) in which thyroid hormones are stored.

Colloid - lumen of each follicle is filled with the gel-like mass called colloid. It is mostly the protein thyroglobulin (pink) and bound thyroid hormones (triiodothyronine and tetraiodothyronine (or thyroxin)). The clear space around the colloid is a shrinkage artifact.
Follicular Cells - follicles are lined by a simple cuboidal to columnar epithelium depending on functional activity. Secrete thyroid hormones when active.
Capillaries - a rich network surrounds each follicle.

Parafollicular Cells (#1 and #2)- small numbers of larger cells located at the periphery of follicles that secrete calcitonin. They stain poorly with H&E making identification difficult.