MHS 209 Thyroid-Parathyroid-Thymus

MICROSCOPE SLIDE

SLIDE NAME

MHS 209 Thyroid-Parathyroid-Thymus

TISSUES

Thyroid
Parathyroid
Thymus

STAIN

Hematoxylin & Eosin

IMAGE SIZE

73,367 x 64,764 pixels
17.7 GB

FILE SIZE

524 MB

MAGNIFICATION

40x

PIXEL SIZE

0.3171 µm

SOURCE

Robert L. Sorenson

CONTACT

Questions or comments should be sent to
tcbrelje@gmail.com

This web site is owned and operated by:

T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Version 4.2

© 2005-2019.
T. Clark Brelje and Robert L. Sorenson.
All rights reserved.

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MHS 209 Thyroid-Parathyroid-Thymus

Thyroid-Parathyroid-Thymus

This specimen is unusual in that a parathyroid gland is embedded within the thyroid which itself is fused with the thymus. This occurs when parts of each tissue fail to migrate to their proper locations during development.

Thyroid

Thyroid Follicles - spherical follicles in which thyroid hormones are stored.

Colloid - lumen of each follicle is filled with the gel-like mass called colloid. It is mostly the protein thyroglobulin (pink) and bound thyroid hormones.
Follicular Cells - follicles are lined by a simple cuboidal to columnar epithelium depending on functional activity. Secrete thyroid hormones when active.

Parafollicular Cells (#1 and #2)- small numbers of larger cells located at the periphery of follicles that secrete calcitonin.

Parathyroid - is composed of only chief cells in juveniles. Oxyphils appear after the first decade of life.

Chief Cells - comprise the majority of cells in the parathyroid and secrete parathyroid hormone (PTH).

Small cells (5 to 8 µm diameter) with dark nuclei and lightly stained cytoplasm.

Oxyphil Cells - only a single cluster of cells is seen. They are larger cells (8 to 12 µm diameter) with dark nuclei and distinctly eosinophilic cytoplasm because of numerous mitochondria.

Thymus