T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Any view of a slide can be saved for later viewing in different ways.
Clipboard
The address of this view has been copied to your clipboard. This link can be pasted in any other program.
Bookmark
A bookmark link can be created using the bookmark function (Ctrl-D for Windows or Cmd-D for Mac) of your browser. Choose a name for the bookmark and select the folder in which you want it saved.
Ultrastructure of a fenestrated capillary showing a single layer of endothelial cells that contain pores (or fenestrations) spanned by a diaphragm (TEM).
Endothelium - one layer of simple squamous epithelial cells
Endothelial cell nuclei are not included in this section
Fenestrations (#1 and #2) - small circular pores (60-80 nm in diameter) that perforate thinner regions of endothelial cells
Spanned by a thin diaphragm that allows passage of small molecules and proteins
Transcytosis - small pinocytotic vesicles (60-80 nm in diameter) transport large molecules in both directions across endothelial cells
Basal Lamina (purple) - separates the capillary from the surrounding connective tissue
Other Cells:
White Blood Cell (tan) - monocyte almost fills the entire lumen of the capillary