T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Mammotrophs are cells in the anterior pituitary that produce prolactin (PRL). They release PRL in response to thyrotropin-releasing hormone and are inhibited by dopamine. Other regulators include estrogen and progesterone. PRL stimulates lactation by the mammary gland.
Mammotrophs during lactation are characterized by large, round to oval secretory granules.