MH 040 Intervertebral Disk

MICROSCOPE SLIDE

SLIDE NAME

MH 040 Intervertebral Disk

TISSUE

Intervertebral Disk

STAIN

Hematoxylin & Eosin

IMAGE SIZE

36,860 x 42,968 pixels
5.9 GB

FILE SIZE

270 MB

MAGNIFICATION

40x

PIXEL SIZE

0.3171 µm

SOURCE

Medical Histology Collection

CONTACT

Questions or comments should be sent to
tcbrelje@gmail.com

This web site is owned and operated by:

T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Version 4.2

© 2005-2019.
T. Clark Brelje and Robert L. Sorenson.
All rights reserved.

HELP

See HELP for more information.

Each slide is shown with additional information to its right. The image can be changed using any combination of the following commands.

Sidebar

Click on links to move to a specific region.
Click on images to show that view.
Use the toolbar to change the magnification and pan the displayed image.

Mouse

Click to zoom-in
Double-click to zoom-out
Alt-click to zoom-out
Alt-double-click to zoom-out to the entire slide
Drag the image to pan

Keyboard

Shift or ‘A’ key to zoom-in
Ctrl or ‘Z’ Key to zoom-out
Arrow Keys to pan across the image
ESC key to zoom-out to the entire slide

Touch

Tap to zoom-in
Double-tap to zoom-out
Alt-tap to zoom-out to the entire slide
Drag the image to pan

SHARE

Any view of a slide can be saved for later viewing in different ways.

Clipboard

The address of this view has been copied to your clipboard. This link can be pasted in any other program.

Bookmark

A bookmark link can be created using the bookmark function (Ctrl-D for Windows or Cmd-D for Mac) of your browser. Choose a name for the bookmark and select the folder in which you want it saved.

Email

This view can be sent by Email to anyone.

MH 040 Intervertebral Disk

Fibrocartilage

Fibrocartilage is a mixture of dense regular connective tissue and hyaline cartilage. It is found in intervertebral discs, pubic symphysis, articular discs and menisci of joints.

Intervertebral discs that are found between adjacent vertebrae of the spine contain fibrocartilage. They have a fibrous appearance of mostly collagen fibers with interspersed areas of cartilage.

(Note that the cytoplasm has been extracted from most of the cells during sample preparation.)

Collagen Fibers - the majority of the fibrocartilage is a mixture of type I and type II collagen. They type I collagen is stained pink/red.
Fibroblasts - scattered cells within fibrous regions with elongated or flattened nuclei. Few are seen in this specimen.
Chondrocytes - are dispersed between collagen fibers singularly, in columns, or in isogenous groups and are surrounded by a basophilic matrix.
Matrix - much less material surrounds each chondrocyte than in hyaline cartilage. It is composed of type II collagen and a ground substance of proteoglycans. The basophilia is due to a high content of sulfated glycosaminoglycans (GAGs).
There is no perichondrium.

Fibrocartilage contains no blood vessels or nerves.