T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Epineurium - dense irregular connective tissue surrounding the entire nerve.
Perineurium - connective tissue surrounding a bundle of nerve fibers (fascicle) within nerves.
Endoneurium - connective tissue surrounding individual nerve fibers within nerves.
Nerve fibers - unmyelinated and myelinated axons of different diameters seen in cross-section.
Axons - light blue material at the center of each nerve fiber.
Schwann Cells - their large, round nuclei are adjacent to some axons. Myelin sheaths appear as pink/red material with radial lines surrounding myelinated axons.
Fibroblasts - their small nuclei are seen in the endoneurium.
Axons - light blue material at the center of each nerve fiber.
Schwann cells - glial cells with large, round to oval nuclei. The myelin sheath appears as striated pink/red material between axons and the endoneurium.
Node of Ranvier - junctions between adjacent Schwann cells surrounding individual axons. Other examples: #1 and #2.
Fibroblasts - elongated nuclei located in the endoneurium.