Histology Guide virtual histology laboratory

Chapter 6 - Nervous Tissue

The nervous system is specialized for communication of information from one region of the body to another.

Nervous system is divided anatomically into two major components:

Nervous system is divided functionally into two major components:

Although the CNS will be briefly examined, most of the emphasize wil be on the PNS.

NEURON

The neuron is the structural and functional unit of the nervous system. However, non-neural cells (i.e., glial cells) provide support and protection in the CNS (oligodendrocytes, astrocytes, ependymal cells and microglia) and the PNS (Schwann cells and satellite cells).

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Fig 017 Motor Neuron

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Fig 016 Types of Neurons

CENTRAL NERVOUS SYSTEM

The central nervous system (CNS) consists of the brain and the spinal cord.

Brain

Neurons have considerable variation in their size and shape. Because of the large size of human brains, the smaller rat brain is examined here.

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MHS 284 Brain

(Golgi's Stain)

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MHS 283 Brain

(Nissl/Chromophil Substance)

Spinal Cord

The spinal cord functions primarily in the transmission of nerve signals between the brain and the body.

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MHS 240 Spinal Cord

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UCSF 163 Spinal Cord

(Nissl/Chromophil Substance)

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MH 047 Spinal Cord

PERIPHERAL NERVOUS SYSTEM

The peripheral nervous system (PNS) consists all nervous tissue outside of the central nervous system.

Dorsal Root Ganglion

Dorsal root ganglia are clusters of nerve bodies of sensory neurons located alongside the spinal cord.

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MH 047 Spinal Cord

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MHS 285-286 Dorsal Root Ganglion

(toluidine blue / myelin stain)

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MH 051 Dorsal Root Ganglion

(azan)

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MH 050 Dorsal Root Ganglion

Sympathetic Ganglion

Sympathetic ganglia form long chains on either side of the spinal cord. They deliver information about stress, impending danger, and the fight-or-flight response.

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MH 047 Spinal Cord

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MH 059 Sympathetic Ganglion

Parasympathetic Ganglion

Parasympathetic nerves have their nerve cell bodies in small ganglia located within the organ they innervate.

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MH 109 Esophagus

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MH 123 Colon

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MHS 211 Pancreas

Peripheral Nerve

Peripheral nerves contain the axons of both motor neurons and sensory neurons that connect with the spinal cord. They are surrounded by multiple layers of connective tissue.

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MH 052 Peripheral Nerve

(longitudinal and cross sections)

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MHS 239 Peripheral Nerve

(Masson's trichrome)

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MH 024 Mesentery

Sensory Nerve Endings

The nervous system has a variety of specialized receptors. Meissner's and Pacinian corpuscles are two that can be readily seen by H&E.

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MH 091 Thick Skin

(Meissner's and Pacinian corpuscles)

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MH 091ahr Thick Skin

(Meissner's corpuscle)

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MH 024 Mesentery

(Pacinian corpuscle)