MH 091 Thick Skin

MICROSCOPE SLIDE

SLIDE NAME

MH 091 Thick Skin

TISSUE

Thick Skin

STAIN

Hematoxylin & Eosin

IMAGE SIZE

44,620 x 28,664 pixels
4.8 GB

FILE SIZE

197 MB

MAGNIFICATION

40x

PIXEL SIZE

0.3171 µm

SOURCE

Medical Histology Collection

Thick skin from the thumb.

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Questions or comments should be sent to
tcbrelje@gmail.com

This web site is owned and operated by:

T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455

Version 4.2

© 2005-2019.
T. Clark Brelje and Robert L. Sorenson.
All rights reserved.

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MH 091 Thick Skin

Mechanoreceptors

A mechanoreceptor is a sensory receptor that responds to mechanical pressure or distortion. Two types are easily seen in skin from fingers or lips.

Meissner's Corpuscle - nerve endings in skin responsible for sensitivity to light touch.

Elliptical structures located in projections of connective tissue (dermal papillae) into the stratified squamous keratinized epithelium (epidermis).
Each corpuscle consists of an unmyelinated axon meandering between Schwann cells arranged as horizontal lamellae surrounded by a connective tissue capsule.
Additional examples: #1, #2, #3 and #4.

Mechanoreceptors

Pacinian Corpuscle - nerve endings in skin responsible for sensitivity to vibration and pressure.

Large oval or spherical structures of 20 to 60 concentric lamellae located in the dense irregular connective tissue (dermis) underneath the epithelium.
Each corpuscle contains an inner bulb of an unmyelinated axon within a fluid-filled cavity formed by several lamellae of Schwann cells. Most of the corpuscle is concentric lamellae separated by fluid. The flattened cells that form these are fibroblasts similar to those located in the endoneurium outside the capsule.
Additional examples: #1 (two Pacinian corpuscles and adjacent nerve) and #2 (two Pacinian corpuscles).