T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Thin skin with cross-sections of hair follicles and their associated sebaceous glands.
Hair Follicles - hair shafts (which are absent in most follicles) are found at the center of hair follicles. These structures are described from the center outwards.
Hair Shaft - cortex and medulla of keratinized cells.
Cuticle - squamous cells form the outermost layer of hair.
Internal Root Sheath - extends from the hair bulb to the level of sebaceous glands.
Huxley's Layer - single or double layer of flattened cells.
Henle's Layer - outer single layer of cuboidal cells.
External Root Sheath - layers of cells continuous with the epidermis.
Glassy membrane - thick basement membrane that separates the hair follicle from the dermis.
Sebaceous Glands - produce a lipid rich secretion called sebum that is released into the hair follicle.
The gland is a cluster of cells with clear cytoplasm because the lipid was extracted during preparation.
Large cells with a central nucleus and a foamy appearing cytoplasm.