T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Hair Shaft - cells grow from the hair bulb, die and lose their cellular detail. The cortex is composed of keratinized cells with melanin, while the medulla contains vacuolated cells.
Cuticle - squamous cells form the outermost layer of hair.
Internal Root Sheath - only extends from the hair bulb to the level of sebaceous glands. The cellular detail also becomes less defined.
Huxley's Layer - single or double layer of flattened cells.
Henle's Layer - outer single layer of cuboidal cells.
Glassy Membrane - thick basement membrane that separates the hair follicle from the dermis.
Hair Bulb - contains a layer of basal epithelial cells that produce the cells that become the hair shaft and the inner root sheath. The epithelium is invaginated by a papilla of connective tissue that brings nutrients to the growing epithelium.
Sebaceous Glands - produce a lipid rich secretion called sebum that is released into the hair follicle. Large cells with a central nucleus and a foamy appearing cytoplasm.
Eccrine Sweat Glands - coiled, tubular sweat-producing glands and ducts with simple or stratified cuboidal epithelium.