T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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A mechanoreceptor is a sensory receptor that responds to mechanical pressure or distortion. Two types are easily seen in skin from fingers or lips.
Meissner's Corpuscles (#1, #2, #3, #4 and #5) - nerve endings in skin responsible for sensitivity to light touch.
Located in dermal papillae.
Each corpuscle consists of an unmyelinated axon meandering between Schwann cells arranged as horizontal lamellae surrounded by a connective tissue capsule.
Pacinian Corpuscles (#1, #2 and #3) - nerve endings in skin responsible for sensitivity to vibration and pressure.
Large oval or spherical structures of 20 to 60 concentric lamellae located in the dense irregular connective tissue (dermis) underneath the epithelium.
Each corpuscle contains an inner bulb of an unmyelinated axon within a fluid-filled cavity formed by several lamellae of Schwann cells. Most of the corpuscle is concentric lamellae separated by fluid. The flattened cells that form these are fibroblasts similar to those located in the endoneurium outside the capsule.