T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
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Connective tissue surrounds nephrons, blood vessels and lymphatics. There is less connective in the cortex compared to the medulla.
Capsule - thin layer of dense irregular connective tissue.
Cortex - connective tissue supports nephrons, blood vessels and lymphatics. Macrophages and fibroblasts are prevalent.
Medulla - connective tissue supports ducts and tubules forming the renal interstitium. The most prevalent connective tissue cell type is myofibroblasts.
Blood Supply - each kidney is supplied by a renal artery.
Interlobar Arteries - branches of the renal artery within the renal sinus that enter the renal columns.
Arcuate Arteries - branches of interlobar arteries that arch over the base of pyramids at the junction of the cortex and medulla.
Interlobular Arteries - branches of arcuate arteries that transverse the cortex to provide an afferent arteriole for each renal corpuscle.
Peritubular Capillaries - destination of efferent arterioles of each renal corpuscle depends on its location.
Peritubular Plexus - efferent arterioles from cortical glomeruli that remain in the cortex.
Medullary Plexus - efferent arterioles from juxtamedular glomeruli that travel through vasa recta in the medulla.