T. Clark Brelje, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Robert L. Sorenson, Ph.D.
University of Minnesota
Department of Genetics, Cell Biology and Development
6-160 Jackson Hall
321 Church St SE
Minneapolis, MN 55455
Any view of a slide can be saved for later viewing in different ways.
Clipboard
The address of this view has been copied to your clipboard. This link can be pasted in any other program.
Bookmark
A bookmark link can be created using the bookmark function (Ctrl-D for Windows or Cmd-D for Mac) of your browser. Choose a name for the bookmark and select the folder in which you want it saved.
Example of a developing bone before replacement of woven immature (or primary) bone with mature (or secondary) bone.
Periosteum - layer of dense irregular connective tissue that covers the outside of bone. It is divided into two layers:
Outer Fibrous Layer - contains fibroblasts that produce the type I collagen on the outer surface of the periosteum.
Inner Osteogenic Layer - contains progenitor cells that can differentiate into osteoblasts. These cells are responsible for increasing the width of bones.
Osteoclasts - large, multinucleated cells that remove bone tissue. They form a resorption bay when attached to bone.
Haversian System - little evidence of osteons characteristic of mature (or secondary) bone. A few developing osteons can be found. Osteons are arranged parallel with the lines of stress in mature bone.